Predicting class II MHC/peptide multi-level binding with an iterative stepwise discriminant analysis meta-algorithm

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Predicting class II MHC/peptide multi-level binding with an iterative stepwise discriminant analysis meta-algorithm

MOTIVATION Predicting peptides that bind to both Major Histocompatibility Complex (MHC) molecules and T cell receptors provides crucial information for vaccine development. An agretope is that portion of a peptide that interacts with an MHC molecule. The identification and prediction of agretopes is the first step towards vaccine design. RESULTS An iterative stepwise discriminant analysis met...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2001

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/17.10.942